Maternal Immunization with Pneumococcal Conjugate Vaccine in the Chinchilla Otitis Media Model ♦ 843
نویسندگان
چکیده
منابع مشابه
Influence of Pneumococcal Conjugate Vaccine on Otitis Media
The vaccine developed for pneumococcal diseases is a heptavalent conjugate vaccine (PCV 7). This particular vaccine consists of capsular polysaccharides originated from seven different Streptococcus pneumoniae species along with the protein diphtheria crm197 as conjugate antigens. In a month time after inoculation in children this vaccine is able to increase the IgG level sufficiently to combat...
متن کاملPneumococcal Conjugate Vaccines and Otitis Media
1Global Vaccine Development, GlaxoSmithKline Vaccines, 1300 Wavre, Belgium 2Department of Pathophysiology and Transplantation, University of Milan and Fondazione IRCCS Cà, Granda Ospedale Maggiore Policlinico, 20122 Milan, Italy 3Paediatric Infectious Diseases, Infection Control and Epidemiology Unit, Université Libre de Bruxelles, 1020 Brussels, Belgium 4Multi-Centre Otitis Media Study Group, ...
متن کاملPneumococcal conjugate vaccine does not influence Staphylococcus aureus carriage in young children with acute otitis media.
We investigated nasopharyngeal carriage of Streptococcus pneumoniae and Staphylococcus aureus among infants and young children with acute otitis media in a country where use of 7-valent pneumococcal conjugate vaccine (PCV7) has been progressively implemented. Among 1783 children enrolled, 60.8% carried S. pneumoniae, and 9% carried S. aureus. Among S. pneumoniae carriers, the rate of S. aureus ...
متن کاملOtitis Media in Fully Vaccinated Preschool Children in the Pneumococcal Conjugate Vaccine Era
Objectives. To evaluate the effect of pneumococcal conjugate vaccine (PCV13) on the burden of acute otitis media (AOM) and to evaluate the characteristics of AOM versus otitis media with effusion (OME) in the 2 PCV periods. Methods. A cohort of fully vaccinated children aged 18 to 60 months diagnosed with AOM from 2006 to 2015 was identified. Patients with otorrhea/bulging tympanic membrane wer...
متن کاملEffect of conjugate pneumococcal vaccine followed by polysaccharide pneumococcal vaccine on recurrent acute otitis media: a randomised study.
BACKGROUND Pneumococcal conjugate vaccine prevents recurrent acute otitis media (AOM) in infants immunised at 2, 4, 6, and 12-15 months of age. We aimed to find out whether this vaccine also prevents AOM in older children who have had previous episodes of AOM. METHODS In this double-blind, randomised study, we enrolled 383 patients aged 1-7 years who had had two or more episodes of AOM in the...
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ژورنال
عنوان ژورنال: Pediatric Research
سال: 1998
ISSN: 0031-3998,1530-0447
DOI: 10.1203/00006450-199804001-00864